BIR: Inhibitor of Apoptosis domain
| PAG Title | BIR: Inhibitor of Apoptosis domain |
| PAG ID | PEX000267 |
| Type | A |
| Source Link |  Pfam |
| Publication Reference | NA |
| PAG Description | BIR stands for Baculovirus Inhibitor of apoptosis protein Repeat. It is found repeated in inhibitor of apoptosis proteins (IAPs), and in fact it is also known as IAP repeat. These domains characteristically have a number of invariant residues, including 3 conserved cysteines and one conserved histidine that coordinate a zinc ion. They are usually made up of 4-5 alpha helices and a three-stranded beta-sheet. BIR is also found in other proteins known as BIR-domain-containing proteins (BIRPs), such as Survivin (Swiss:O15392) 2. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 0 |
| Information Content | Poor |
| Other IDs | PF00653 |
| Base PAG ID | PEX000267 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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